Complementary Food to Improving HDL & LDL in Malnourished Male Wistar Strain White Rats

Biology Department, Universitas Negeri Malang, 65145 Malang, Indonesia

^* Corresponding author : yunita.rakhmawati.fmipa@um.ac.id

Abstract

Protein-energy malnutrition (PEM) causes a decrease in amino acid synthesis, which affects the decrease in High-Density Lipoprotein (HDL) levels and an increase in Low-Density Lipoprotein (LDL) levels. Improving HDL and LDL levels in malnourished can be managed by providing Complementary Food (CF) with main ingredients such as banana flour, cassava flour, and corn flour. This study aims to describe the effect of CF supplementation on the HDL and LDL levels of malnourished male Wistar rats. The research method was experimental with a Randomized Block Design using twenty-four male rats. The experimental animals were divided into six treatment groups and carried out for 4 weeks. Data on HDL and LDL levels were obtained from rat blood serum detected by spectrophotometer and analysed by ANOVA. The results showed significant differences in HDL levels with the administration of CF (P < 0.05) and no significant differences in LDL levels with CF supplementation (P > 0.05). CF can increase HDL levels and tend to decrease LDL levels.