The Complementary Food for Intestine Microanatomy Amelioration of the Malnourished Rats (Rattus norvegicus)

Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Negeri Malang, Jl. Semarang No. 5, Malang 65145, Indonesia

^* Corresponding author : yunita.rakhmawati.fmipa@um.ac.id

Abstract

Protein Energy Malnutrition (PEM) is insufficient animal or vegetable protein consumption in daily food. PEM can result in damage to intestinal cells, which causes villous atrophy, decreased crypt depth, and a decrease in the number of epithelial cells, which results in failure to absorb nutrients. CF can be used to stimulate growth, improve inflammation and improve intestinal microbiota. This study, crucial for understanding the impact of CF on PEM, aims to describe the microanatomy of small intestine (jejunum) mice (Rattus norvegicus) PEM after giving CF. The research method was experimental with a Randomized Block Design (RBD) using 24 mice. The experimental animals were divided into 6 groups: the control and treatment groups with complementary food with various carbohydrate sources. Treatment was carried out for 4 weeks. Data in microanatomy and small intestinal villi height resulted in the highest villous rate height in the K+P0 group and the lowest in the K- group. The results showed that administration of CF did not show a significant results (P < 0.05) on the height of the villi of the small intestine (jejunum).