| Issue |
BIO Web Conf.
Volume 130, 2024
International Scientific Conference on Biotechnology and Food Technology (BFT-2024)
|
|
|---|---|---|
| Article Number | 04009 | |
| Number of page(s) | 5 | |
| Section | Medical Biotechnology and Community Health | |
| DOI | https://doi.org/10.1051/bioconf/202413004009 | |
| Published online | 09 October 2024 | |
Human growth hormone produced with recombinant DNA technology
Jizzakh branch of the National University of Uzbekistan, Jizzakh, Uzbekistan
* Corresponding author: mmustafakulov@bk.ru
Hormones affect the metabolism by stimulating the genetic apparatus of the cell, activating enzymes and changing the rate of enzymatic reactions. They increase the formation of informative ribonucleic acid, which determines the structure of the protein, and affect the biosynthesis of proteins. Somatotropin hormone (STG) is a peptide hormone consisting of 192 amino acids and is secreted from the anterior lobe of the pituitary gland. The deficiency of this hormone causes hypophysis. The demand for recombinant somatotropin is likely to increase in the near future. Because current production technologies cannot meet the demand for cheap somatotropin due to limited production capacity and high production cost. As a result, it is necessary to study the mechanisms of production of therapeutic recombinant proteins. Recombinant somatotropin is mainly synthesized using E. coli lemo strain and is used for therapeutic purposes.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.