| Issue |
BIO Web Conf.
Volume 142, 2024
2024 International Symposium on Agricultural Engineering and Biology (ISAEB 2024)
|
|
|---|---|---|
| Article Number | 03002 | |
| Number of page(s) | 5 | |
| Section | Microbial Engineering and Biomedical Exploration | |
| DOI | https://doi.org/10.1051/bioconf/202414203002 | |
| Published online | 21 November 2024 | |
The Cellular and Molecular Biology of Aging
School of Lifesciences, University of Warwick, Coventry, West Midlands, CV4 7AL, UK
* Corresponding author: Ergaosi.mo@gmail.com
Aging is characterized as a complex biological process, marked by a progressive diminution in physiological capacities and an escalated susceptibility to diverse diseases. This trajectory detrimentally affects individual well-being and exerts considerable strain on healthcare frameworks and economic stability. Effective methods to prevent and reverse aging have been explored in academic research and clinical settings for a long time. However, the long-term effectiveness and safety of anti-aging measures still need to be further verified. This article provides insight into specific biological mechanisms associated with aging, such as genomic instability, telomere dysfunction, epigenetic modifications, and mitochondrial dysfunction. In addition, the complex role of autophagic activity, senescence-associated secretory phenotypes and epigenetics with aging is also discussed, emphasizing the importance of understanding these processes for aging interventions.
© The Authors, published by EDP Sciences, 2024
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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