| Issue |
BIO Web Conf.
Volume 147, 2024
11th International Symposium of East Asia Fisheries and Technologist Association (EAFTA 2024)
|
|
|---|---|---|
| Article Number | 01007 | |
| Number of page(s) | 14 | |
| DOI | https://doi.org/10.1051/bioconf/202414701007 | |
| Published online | 10 January 2025 | |
Diversity and antibacterial potential produced by marine endophytic fungi by submerged fermentation from Buton Island, Indonesia
1 Department of Aquatic Product Technology, Faculty of Fisheries and Marine Science, IPB University, Jl. Agatis, 16680, Bogor, Indonesia
2 Division of Marine Biotechnology, Center for Coastal and Marine Resources Studies (PKSPL), International Research Institute for Maritime, Ocean and Fisheries (i-MAR), IPB University, 16127, Bogor, Indonesia
3 Department of Marine Biotechnology, Tual State Fisheries Polytechnic, Jl. Raya Langgur, 97611, Maluku, Indonesia
4 Department of Aquaculture, Faculty of Fisheries and Marine Science, IPB University, Faculty of Fisheries and Marine Science, IPB University, Jl. Agatis, 16680, Bogor, Indonesia
5 College of Engineering, National Chung Cheng University, 62102, Chiayi County, Taiwan
6 Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Universitas Gadjah Mada, 55281, Yogyakarta, Indonesia
7 Department of Pharmacology, Faculty of Pharmacy, Hasanuddin University, Makassar, 90245, Indonesia
8 Doctoral Program in Natural Resources and Environmental Management Science (NREMS), Graduate School of IPB University, School Building Floor II IPB Baranangsiang, 16144, Bogor Indonesia
9 Research Center for Marine and Land Bioindustry, National Research and Innovation Agency, Laterio Building, 14430, Jakarta, Indonesia
* Corresponding author: kustiaz@apps.ipb.ac.id
This study investigated the diversity and antibacterial potential of marine endophytic fungi from Buton Island, Indonesia. This study focused on identifying fungi capable of producing bioactive compounds effective against Vibrio harveyi. 32 fungal isolates were obtained from various marine samples. Aspergillus terreus (WB 1-2) exhibited the highest antibacterial activity. The growth dynamics of these fungi were analyzed, emphasizing the importance of the log phase for secondary metabolite production. Environmental conditions and mechanical agitation were found to significantly influence growth and metabolite yield. These findings highlight the potential of marine endophytic fungi as sources of novel antimicrobial agents, suggesting promising opportunities for biotechnological and pharmaceutical advancements. This study underscores the untapped potential of marine fungi for the development of new antibiotics.
© The Authors, published by EDP Sciences, 2024
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