Issue |
BIO Web Conf.
Volume 152, 2025
International Conference on Health and Biological Science (ICHBS 2024)
|
|
---|---|---|
Article Number | 01002 | |
Number of page(s) | 14 | |
Section | Dense Matter | |
DOI | https://doi.org/10.1051/bioconf/202515201002 | |
Published online | 20 January 2025 |
Neuro-inflammation, depression and fatigue in ESRD: Emerging role of microglia and acupuncture as a new treatment addressing neuro-inflammation in ESRD
1 Anesthesiology Nursing Study Program, Faculty of Health, Universitas Harapan Bangsa, Indonesia
2 The Graduate Institute of Clinical Medicine Science, College of Medicine, Chang Gung University, Tao-Yuan, Taiwan
3 School of Nursing, Faculty of Health, Universitas Harapan Bangsa, Central Java, Indonesia
* Corresponding author: madesuandika@uhb.ac.id
ESRD is the most serious form of CKD and is frequently associated with a variety of complications, including depression and fatigue. These diseases contribute to higher morbidity and death among ESRD patients. Chronic inflammation and other pathological factors contribute to the occurrence of both of the aforementioned consequences. The purpose of this study is to propose that neuroinflammation-induced microglial activation may play an important role in these circumstances. Their interplay also provides new avenues for improving palliative care. The method employed combines a literature review with a narrative review to provide an evaluation of the connection of low-grade systemic inflammation with depression and overload in ESRD patients. The findings of this review show that depressive symptoms and fatigue are common in ERDS patients. Acupuncture, as a non-pharmacological option, has been shown to reduce chronic inflammation and enhance clinical results for ERSD patients’ quality of life. In conclusion, acupuncture is showing promise as treatment because they can alter neuroinflammatory pathways and lessen symptoms.
© The Authors, published by EDP Sciences, 2025
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.