Issue |
BIO Web Conf.
Volume 154, 2025
15th International Conference on Global Resource Conservation (ICGRC 2024) in conjunction with the 1st International Conference on Jamu and Alternative Medicine (ICJAM 2024)
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Article Number | 04003 | |
Number of page(s) | 7 | |
Section | Jamu Processing Technology | |
DOI | https://doi.org/10.1051/bioconf/202515404003 | |
Published online | 28 January 2025 |
The synthesis of chitosan-sodium tripolyphosphate nanoparticles for delivery of Ocimum africanum extract
1 Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Malang, East Java, Indonesia
2 Department of Socio-Economic Agriculture, Faculty of Agriculture, Brawijaya University, 65145, Malang, East Java, Indonesia
3 Program Study of Pharmacy, Pharmacy Academy of Surabaya, 60232, Surabaya, East Java, Indonesia
4 Doctoral program of Biology, Department of Biology, Faculty of Mathematics and Natural Sciences, Brawijaya University, Malang, East Java, Indonesia
* Corresponding author: srahayu@ub.ac.id
The aim of the present work is to obtain Ocimum africanum extract nanoparticles (OaE-NPs) that have been crosslinked via ionic gelation with chitosan (chi) and sodium tripolyphosphate (TPP). Nanoencapsulation will enable investigation of the morphology profile and size of OaE-NPs. The OaE-NPs produced via ionic gelation exhibited a 6.4 nm in size and a low polydispersity index (PDI) of 0.177. Additionally, SEM observation revealed that the surface shape of OaE-NPs was a loose aggregate with an uneven surface. These findings provide a simple and reliable approach for generating nanoparticles from O. africanum coated with chitosan/TPP.
© The Authors, published by EDP Sciences, 2025
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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