Issue |
BIO Web Conf.
Volume 155, 2025
10th-ICCC – 10th International Conference on Climate Change “Climate Change, Plant and Health”
|
|
---|---|---|
Article Number | 10004 | |
Number of page(s) | 14 | |
Section | Climate Change Impact on Health and Adaptation/Mitigation Strategy | |
DOI | https://doi.org/10.1051/bioconf/202515510004 | |
Published online | 29 January 2025 |
Association between air pollution and osteoporosis: A systematic review
1 Doctoral Program of Medical Sciences, Faculty of Medicine, Universitas Sebelas Maret, 57126, Surakarta, Indonesia
2 Obstetrics and Gynecology Department, Faculty of Medicine, Universitas Sebelas Maret, 57126, Surakarta, Indonesia
3 Biochemistry Department, Faculty of Medicine, Universitas Sebelas Maret, 57126, Surakarta, Indonesia
4 Clinicopathologic Department, Faculty of Medicine, Universitas Sebelas Maret, 57126, Surakarta, Indonesia
5 Public Health Department, Faculty of Medicine, Universitas Sebelas Maret, 57126, Surakarta, Indonesia
6 Internal Medicine Department, Faculty of Medicine, Universitas Sebelas Maret, 57126, Surakarta, Indonesia
7 Parasitology Department, Faculty of Medicine, Universitas Sebelas Maret, 57126, Surakarta, Indonesia
* Corresponding author: dr.Nurhasan21@staff.uns.ac.id
Background: Osteoporosis is a major worldwide health problem associated with lower bone mineral density (BMD) and higher fracture risk, which contributes to increased morbidity and healthcare costs. Meanwhile, some modifiable environmental factors affect bone health, including air pollution and smoking. Objective: The current systematic review aims to summarize the available data regarding the impact of air pollution and smoking on osteoporosis. Methods: A systematic search of the observational studies published from 2000 to 2024 was performed in PubMed. ROBINS-I identified twenty-one studies based on the inclusion criteria and assessed the quality. Results: For exposure to particulate matter (PM2. 5, PM10), nitrogen oxides (NO₂) and smoking were associated with lower BMD and increased fracture risk. These mechanisms include oxidative stress, systemic inflammation, and heavy metal toxicity in women disproportionately, older adults and urban populations. Conclusion: Further public health efforts, such as regulating air quality imbalance and developing social willingness to quit smoking, shall be called upon to alleviate osteoporosis burdens and promote bone health worldwide.
Key words: Osteoporosis / Air pollutants / Smoking / Bone density / public health
© The Authors, published by EDP Sciences, 2025
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.