| Issue |
BIO Web Conf.
Volume 205, 2025
2025 10th International Conference on Energy Efficiency and Agricultural Engineering (EE&AE 2025)
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|
|---|---|---|
| Article Number | 01024 | |
| Number of page(s) | 9 | |
| DOI | https://doi.org/10.1051/bioconf/202520501024 | |
| Published online | 16 December 2025 | |
ADME potential of porphyrin derivative from petroleum
1 Department of Chemistry, Burgas State University “Prof. Dr. Assen Zlatarov”, Burgas 8010, Bulgaria
2 “LUKOIL Neftochim Burgas” AD, Burgas, Bulgaria
3 Burgas State University “Prof. Dr. Assen Zlatarov”, Burgas 8010, Bulgaria
* Corresponding author: This email address is being protected from spambots. You need JavaScript enabled to view it.
Chlorins are tetrapyrrole pigments that are formally described as partially hydrogenated porphyrins, specifically dihydroporphyrins. This structural difference gives them distinct chemical and photophysical properties that are essential for their biological functions and applications. Chlorins are excellent photosensitizing agents. The most well-known examples of naturally occurring chlorins are the chlorophylls, which are magnesium-containing chlorin derivatives found in plants and bacteria. The structural alteration (partial hydrogenation) of the macrocycle is crucial for photosynthesis. Microbes produce two major reduced variants of the chlorin macrocycle, both of which contain two reduced pyrrole rings (tetrahydroporphyrins) and are crucial for various metabolic and photosynthetic processes: bacteriochlorins and isobacteriochlorins. The present study aims to use an in silico approach to predict the biological effects of a specific chlorin derivative.
© The Authors, published by EDP Sciences, 2025
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