| Issue |
BIO Web Conf.
Volume 214, 2026
The 2025 International Conference on Biomedical, Bioinformatics and Statistics (ICBBS 2025)
|
|
|---|---|---|
| Article Number | 01010 | |
| Number of page(s) | 5 | |
| Section | Biomedical, Bioinformatics and Statistics | |
| DOI | https://doi.org/10.1051/bioconf/202621401010 | |
| Published online | 02 February 2026 | |
Extraction of Active Components from Ziziphus jujuba var. spinosa and Development of Insomnia-Improving Products
Shanghai Ocean University, No. 999, Hucheng Huan Road, Nanhui New Town, Pudong New Area, Shanghai, 201306, China
* Corresponding author: This email address is being protected from spambots. You need JavaScript enabled to view it.
Insomnia, a prevalent global health issue exacerbated by modern life stress, affects 38.2% of Chinese people, with a rising trend among youth. Ziziphus jujuba Mill. var. spinosa (Bunge) Hu ex H. F. Chou, rich in saponins and flavonoids, exhibits sedative-hypnotic and anti-anxiety effects, offering a natural solution for insomnia. This study explores the potential of saponin-based substances from medicinal plants (e.g., Z. jujuba var. spinosa, Panax notoginseng) for sleep improvement. It systematically analyzes the technological evolution in transforming saponin-containing materials into modern preparations, including multidimensional raw material identification (DNA barcoding, NIRS, ICP-MS) and advancements in extraction technologies. Challenges remain, such as high costs of supercritical CO2 extraction, unclear sleep-regulating mechanisms of saponins, and formulation optimization hurdles. This work provides a foundation for developing safe, eco-friendly saponin-derived sleep-aiding products.
© The Authors, published by EDP Sciences, 2026
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.