Open Access
Table 2.
The dynamics of expression of hepatocyte marker genes.
| Hepatocyte marker gene | Day after transfection | |||
|---|---|---|---|---|
| 6 | 12 | 21 | 42 | |
| Beta actin | 0,32±0,1 | 4,12+0,34* | 4,59±0,29* | 4,45±0,28* |
| Alpha fetoprotein | 0,68±0,06 | 7,88±0,39* | 3,14±0,55* | 2,53±0,62* |
| Cytokeratin 18 | 2,57±0,21 | 3,11±0,42 | 6,57±0,46* | 9,18±0,39* |
| Albumen | 2,72±0,07 | 4,13±0,33* | 5,41±0,35* | 6,22±0,38* |
| Tryptophan 2,3-Dioxigenase | 2,12±0,09 | 4,52±0,36* | 5,88±0,51* | 5,42±0,51* |
| Tyrosinaminotransferase | 0,11±0,03 | 0,12±0,08 | 7,88±0,54* | 9,69±0,72* |
| Alpha 1 Antitrypsin | 1,54±0,17 | 2,86±0,32* | 3,89±0,55* | 4,78±0,64* |
| Glucuronisiltransferase 1A | 3,1±0,13 | 2,99±0,25 | 3,45±0,62 | 4,01±0,4*7 |
| Hepatocyte Nuclear Factor 4 alpha | 0,44±0,12 | 2,89±0,24* | 3,46±0,49* | 5,47±0,42* |
| Cytochrome P450 3A4 | 0,13±0,01 | 1,01±0,2* | 5,55±0,41* | 6,27±0,38* |
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