Table 1.
The characteristics of the rats cardiorespiratory system after injecting the acetylsalicylic acid and acetylsalicylates of Ni2+ and Mn2+ in different concentrations
| Group | SBP, mm m.c.. | DBP, mm.m.c. | HR, b./min | RR, r.r./min | |
|---|---|---|---|---|---|
| Control (1) | 113.4±1.32 | 72.20±0.91 | 378.4±15.23 | 109.67±4.38 | |
| The acetylsalicylic acid | 5 mg/kg (2) | 114.6±1.18 | 70.7±1.07 | 334.8±16.7 1≤0.05 | 109.9±3.59 |
| 10mg/kg (3) | 112±1.18 | 70.07±0.94 | 347.63±6.3 p1≤0.05 | 106.8±4.38 | |
| ACMn2+ | 5mg/kg (4) | 114.60±1.94 | 75.73±1.25 p1≤0.05 p2≤0.05 | 396.13±11.85 p1≤0.05 | 126.07±8.26 p1≤0.05 p2≤0.05 p5≤0.05 p6≤0.05 |
| 10mg/kg (5) | 112.40±2.08 | 75.07±0.79 p2≤0.05 | 406.73±9.86 p1≤0.05 p2≤0.05 p7≤0.05 | 94.53±1.79 p1≤0.05 p2≤0.05 p4≤0.05 p7≤0.05 | |
| ACNi2+ | 5 mg/kg (6) | 113.73±1.95 | 73.53±1.07 p2 ≤0.05 | 412.87±16.56 p7≤0.05 | 93.13±2.71 p1≤0.05 p4≤0.05 p7≤0.05 |
| 10mg/kg (7) | 111.20±2.09 | 75.67±1.08 p2≤0.05 | 333.13±12.89 p5≤0.05 p6≤0.05 | 81.00±2.16 p1≤0.05 p2≤0.05 p5≤0.05 p6≤0.05 | |
Note: М is an average arithmetic value, М±m is an error of mean, p 1-7 is the confidence level of indices difference according to Mann-Whitney test concerning the corresponding animal groups; SBP is a systolic blood pressure; DBP is a diastolic blood pressure; HR is heart rate; RR is a respiratory rate
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