Molecular Action of Herbal Medicine in Physiology of Erection and its Dysfunction

Open Access

Issue		BIO Web Conf. Volume 49, 2022 The 3^rd International Symposium on Global Physiology 2022 (ISGP 2022)


Article Number		02002
Number of page(s)		8
Section		Cellular and Molecular Physiology
DOI		https://doi.org/10.1051/bioconf/20224902002
Published online		05 July 2022

M.F. van Driel. Sex Med. 3, 4:349-57 (2015) [CrossRef] [PubMed] [Google Scholar]
A. Muneer, J. Kalsi, I. Nazareth, M. Arya. BMJ. 348, g129 (2014) [CrossRef] [PubMed] [Google Scholar]
D.K. Montague, J.P. Jarow, G.A. Broderick, R.R. Dmochowski, J.P. Heaton, T.F. Lue, et al. J Urol. 174, 1:230-9 (2005) [CrossRef] [PubMed] [Google Scholar]
K. Hatzimouratidis, E. Amar, I. Eardley, F. Giuliano, D. Hatzichristou, F. Montorsi. Eur. Urol. 57, 5:804-14 (2010) [CrossRef] [Google Scholar]
G. Lombardi, F. Nelli, M. Celso, M. Mencarini, G. Del Popolo. J Sex Med. 9, 4:970-85 (2012). [CrossRef] [PubMed] [Google Scholar]
A. Kessler, S. Sollie, B. Challacombe, K. Briggs, M. Van Hemelrijck. BJU Int. (2019) [Google Scholar]
O.A. Orimoloye, D.I. Feldman, M.J. Blaha. Trends Cardiovasc. Med. 29, 8:458-65 (2019) [CrossRef] [Google Scholar]
B. Nisahan, T. Kumanan, N. Rajeshkannan, T. Peranantharajah, M. Aravinthan. BMC Res Notes. 12, 1:210- (2019) [CrossRef] [PubMed] [Google Scholar]
K.H. Moon, S.Y. Park, Y.W. Kim. World J Mens Health. 37, 2:138-47 (2019) [CrossRef] [PubMed] [Google Scholar]
RC. Rosen, JR. Heiman, JS. Long, WA. Fisher, MS. Sand. Arch. Sex. Behav. 45, 1:159-73 (2016) [CrossRef] [PubMed] [Google Scholar]
P.A. Agaba, A.N. Ocheke, M.O. Akanbi, Z.M. Gimba, J. Ukeagbu, B.D. Mallum, et al. Niger Med J. 58, 3:96-100 (2017) [CrossRef] [PubMed] [Google Scholar]
V.J. Sin, GS. Anand, H.L. Koh. Sex. Med. Rev. 9, 4:568-92 (2021) [CrossRef] [Google Scholar]
N. Malviya, S. Jain, VB. Gupta, S. Vyas. Acta Pol. Pharm. 68, 1:3-8 (2011) [Google Scholar]
P.K. Panchatsharam, J. Durland, P.M. Zito. Physiology, Erection. StatPearls. Treasure Island (FL): StatPearls Publishing Copyright © 2021, StatPearls Publishing LLC. (2021) [Google Scholar]
S.A. Raeissadat, A. Javadi, F. Allameh. Vasc. Health Risk Manag. 14:393-9 (2018) [CrossRef] [Google Scholar]
J.G. Chen, R. Jiang. Zhonghua nan ke xue = Natl. j. androl. 24, 2:172-5 (2018) [Google Scholar]
F. Qin, L. Gao, S. Qian, F. Fu, Y. Yang, J. Yuan. Int J Impot Res. 30, 4:192-201 (2018) [CrossRef] [PubMed] [Google Scholar]
R.S. Calabrò, G. Gervasi, A. Naro, R. de Luca, M. Marullo, P. Bramanti. Innov Clin Neurosci. 13, 1-2:10-4 (2016) [Google Scholar]
A.L. Burnett. Trans Am Clin Climatol Assoc. 130:51-9 (2019) [PubMed] [Google Scholar]
N.A. Sopko, J.L. Hannan, T.J. Bivalacqua. Nat Rev Urol. 11, 11:622-8 (2014) [CrossRef] [PubMed] [Google Scholar]
G. Lu, T.W. Hein, L. Kuo. Transl. Biomed. 1, 2 (2010) [Google Scholar]
E.G. Cameron, M.S. Kapiloff. Neural Regen. Res. 12, 2:201-2 (2017) [CrossRef] [PubMed] [Google Scholar]
K.J. Hurt, S.F. Sezen, G.F. Lagoda, B. Musicki, G.A. Rameau, S.H. Snyder, et al. Cyclic AMPdependent phosphorylation of neuronal nitric oxide synthase mediates penile erection, in Proceedings of the National Academy of Sciences of the United States of America. 109, 41:16624-9 (2012) [Google Scholar]
H. Matsui, N.A. Sopko, J.L. Hannan, T.J. Bivalacqua. Curr. Drug Targets. 16, 5:411-9 (2015) [CrossRef] [Google Scholar]
Y. Kouidrat, D. Pizzol, T. Cosco, T. Thompson, M. Carnaghi, A. Bertoldo, et al. Diabet Med. 34, 9:1185-92 (2017) [CrossRef] [PubMed] [Google Scholar]
R.S. Frey, M. Ushio-Fukai, A.B. Malik. Antioxid. Redox Signal. 11, 4:791-810 (2009) [CrossRef] [PubMed] [Google Scholar]
L.M. Jin. J Sex Med. 6 Suppl 3:302-10 (2009) [CrossRef] [PubMed] [Google Scholar]
M. Baumhäkel, N. Schlimmer, M. Böhm. Int. J. Impot. Res. 20, 5:493-500 (2008) [CrossRef] [PubMed] [Google Scholar]
Z. Ding, X. Shen, Y. Li. Exp Ther Med. 13, 3:1133-6 (2017) [CrossRef] [PubMed] [Google Scholar]
A.V. Schofield, R. Steel, O. Bernard. J. Biol. Chem. 287, 52:43620-9 (2012) [CrossRef] [Google Scholar]
G. Loirand. Pharmacol. Rev. 67, 4:1074-95 (2015) [CrossRef] [PubMed] [Google Scholar]
Q. Zhou, Y. Mei, T. Shoji, X. Han, K. Kaminski, G.T. Oh, et al. Circulation. 126, 18:2236-47 (2012) [CrossRef] [PubMed] [Google Scholar]
T. Trepels, A.M. Zeiher, S. Fichtlscherer. Endothelium-J Endoth. 13, 6:423-9 (2006) [CrossRef] [PubMed] [Google Scholar]
S. Chia, M. Qadan, R. Newton, C.A. Ludlam, K.A. Fox, D.E. Newby. Arterioscler Thromb Vasc Biol. 23, 4:695-701 (2003) [CrossRef] [PubMed] [Google Scholar]
H.D. Anderson, D. Rahmutula, D.G. Gardner. J. Biol. Chem. 279, 2:963-9 (2004) [CrossRef] [Google Scholar]
P. Neumann, N. Gertzberg, A. Johnson. Am. J. Physiol. Lung Cell Mol. Physiol. 286, 2: L452-9 (2004) [CrossRef] [PubMed] [Google Scholar]
M. Yoshizumi, M.A. Perrella, J.C. Burnett, Jr., M.E. Lee. Circ. Res. 73, 1:205-9 (1993) [CrossRef] [PubMed] [Google Scholar]
H. Wang, F. Xu, X. Wang, W.S. Kwon, D.C. Yang. J. Ginseng Res. 43, 3:482-7 (2019) [CrossRef] [Google Scholar]
Y.J. Kim, D. Zhang, D.C. Yang. Biotechnol. Adv. 33, 6 Pt 1:717-35 (2015) [CrossRef] [Google Scholar]
K.T. Choi. Acta Pharmacol. Sin. 29, 9:1109-18 (2008) [CrossRef] [Google Scholar]
P. Mohanan, S. Subramaniyam, R. Mathiyalagan, D.C. Yang. J. Ginseng Res. 42, 2:123-32 (2018) [CrossRef] [Google Scholar]
J.S. Lee, H.S. Choi, S. W. Kang, J.H. Chung, H.K. Park, J.Y. Ban, et al. Am. J. Chinese Med. 39, 1:83-94 (2011) [CrossRef] [PubMed] [Google Scholar]
T. Ramesh, S.W. Kim, S.Y. Hwang, S.H. Sohn, S.K. Yoo, S.K. Kim. Nutr Res. 32, 9:718-26 (2012) [CrossRef] [PubMed] [Google Scholar]
D.J. Jang, M.S. Lee, B.C. Shin, Y.C. Lee, E. Ernst. Br. J. Clin. Pharmacol. 66, 4:444-50 (2008) [CrossRef] [Google Scholar]
K.W. Leung, A.S. Wong. Spermatogenesis. 3, 3: e26391 (2013) [CrossRef] [PubMed] [Google Scholar]
G.B. Mahady, C. Gyllenhaal, H.H. Fong, N.R. Farnsworth. Nutr Clin Care. 3, 2:90-101 (2000) [CrossRef] [Google Scholar]
WHO. WHO monographs on selected medicinal plants: World Health Organization (1999) [Google Scholar]
F. Siraj, Y.J. Kim, S. Natarajan, S. Jung, D. Yang, D.C. Yang. Food Sci. Biotechnol. 23, 1007-16 (2014) [CrossRef] [Google Scholar]
L.W. Qi, C.Z. Wang, C.S. Yuan. Nat. Prod. Rep. 28, 3:467-95 (2011) [CrossRef] [PubMed] [Google Scholar]
J. Yu, M. Eto, M. Akishita, O. Kaneko, Y. Ouchi, T. Okabe. Biochem. Biophys. Res. Commun. 353, 3:764-9 (2007) [CrossRef] [Google Scholar]
K.W. Leung, Y.K. Cheng, N.K. Mak, K.K. Chan, T.P Fan, R.N. Wong. FEBS lett. 580, 13:3211-6 (2006) [CrossRef] [PubMed] [Google Scholar]
X. Wang, S. Chu, T. Qian, J. Chen, J. Zhang. J Sex Med. 7, 2, Part 1:743-50 (2010) [CrossRef] [PubMed] [Google Scholar]
Y.J. Kang, J.T Sohn, K.C. Chang. Life Sci. 77, 1:74-84 (2005) [CrossRef] [PubMed] [Google Scholar]
H. Lee, J.S. Birks. Cochrane Database Syst Rev. 2018, 8:CD004671 (2018) [Google Scholar]
F. Drago, M.L. Floriddia, M. Cro, S. Giuffrida. J Ocul Pharmacol Ther. 18, 2:197-202 (2002) [CrossRef] [PubMed] [Google Scholar]
H.J. Liao, Y.F. Zheng, H.Y. Li, G.P. Peng. Planta med. 77, 16:1818-21 (2011) [CrossRef] [PubMed] [Google Scholar]
A. Tashima. Front Pharmacol. 10 (2019) [PubMed] [Google Scholar]
X. Zhang, Y. Li, L. Zhang, M. Qin. J. China Pharm. Univ. 40, 4:306-9 (2009) [Google Scholar]
W. You, Z. Wu, F. Ye, X. Wu. Pharmazie. 74, 11:698-702 (2019) [PubMed] [Google Scholar]
S. Gauthier, S. Schlaefke. Clin Interv Aging. 9, 2065-77 (2014) [CrossRef] [PubMed] [Google Scholar]
C. Wang, B. Wang. Phytother Res. 30, 5:774-80 (2016) [CrossRef] [PubMed] [Google Scholar]
G. Siegel, E. Ermilov, O. Knes, M. Rodríguez. Atherosclerosis. 237, 2:584-8 (2014) [CrossRef] [PubMed] [Google Scholar]
B.A. Abdel-Wahab, S.M. Abd El-Aziz. Phytomedicine. 19, 5:444-50 (2012) [CrossRef] [PubMed] [Google Scholar]
T. Long, G. Liu, Y. Wang, Y. Chen, Y. Zhang, D. Qin. J Sex Med. 9, 7:1801-14 (2012) [CrossRef] [PubMed] [Google Scholar]
B. Musicki, J.L. Hannan, G. Lagoda, T.J. Bivalacqua, A.L. Burnett. Andrology. 4, 5:977-83 (2016) [CrossRef] [PubMed] [Google Scholar]
G.G. Wang, Q.Y. Chen, W. Li, X.H. Lu, X. Zhao. Croat Med J. 56, 1:4-13 (2015) [CrossRef] [PubMed] [Google Scholar]
K. Nakashima, H. Miyashita, H. Yoshimitsu, Y. Fujiwara, R. Nagai, T. Ikeda. J Nat Med. 70, 2:290-5 (2016) [CrossRef] [PubMed] [Google Scholar]
X.J. Chen, Z.H. Tang, X.W. Li, C.X. Xie, J.J. Lu, Y.T. Wang. Am J Chin Med. 43, 5:783-834 (2015) [CrossRef] [PubMed] [Google Scholar]
Q. Zhong-zhi, D. Yang, L. Yan-ze Liu, P. Yong. Chin. Herb. Med. 2, 2:157-9 (2010) [Google Scholar]
H.K. Kang, Y.H. Choi, H. Kwon, S.B. Lee, D.H. Kim, C.K. Sung, et al. Food Chem. Toxicol. 50, 8:2751-9 (2012) [CrossRef] [Google Scholar]
M.N. Makarova, O.N. Pozharitskaya, A.N. Shikov, S.V. Tesakova, V.G. Makarov, V.P. Tikhonov. J Ethnopharmacol. 114, 3:412-6 (2007) [CrossRef] [PubMed] [Google Scholar]
L. Cui, E. Sun, Z.H. Zhang, X.B. Tan, Y.J. Wei, X. Jin, et al. Molecules. 17, 12984-96 (2012) [CrossRef] [PubMed] [Google Scholar]
J. Fang, Y. Zhang. Front Pharmacol. 8, 734- (2017) [CrossRef] [PubMed] [Google Scholar]
M.H. Kwon, S.H. Park, K.M. Song, K. Ghatak, A. Limanjaya, D.S. Ryu, et al. Int J Urol. 23, 7:614-22 (2016) [CrossRef] [PubMed] [Google Scholar]
B.H. Chung, J.D. Kim, C.K. Kim, J.H. Kim, M.H. Won, H.S. Lee, et al. Biochem Biophys Res Commun. 376, 2:404-8 (2008) [CrossRef] [PubMed] [Google Scholar]
S.J. Lee, S. Namkoong, Y.M. Kim, C.K. Kim, H. Lee, K.S. Ha, et al. Am J Physiol Heart Circ Physiol. 291, 6 (2006) [Google Scholar]
G. Dong, Z. Chen, Z.Y. Li, N.T. Yeh, C.C. Bancroft, C. Van Waes. Cancer res. 61, 15:5911-8 (2001) [PubMed] [Google Scholar]
S. Namkoong, B.H. Chung, K.S. Ha, H. Lee, Y.G. Kwon, Y.M. Kim. Methods Enzymol. 441, 393-402 (2008) [CrossRef] [PubMed] [Google Scholar]
A.W. Shindel, Z.C. Xin, G. Lin, T.M. Fandel, Y.C. Huang, L. Banie, et al. J. Sex. Med. 7, 4 Pt 1:1518-28 (2010) [CrossRef] [Google Scholar]
R. Liu, J.P. Jin. Gene. 585, 1:143-53 (2016) [CrossRef] [PubMed] [Google Scholar]
H. Takooree, M.Z. Aumeeruddy, K.R.R. Rengasamy, K.N. Venugopala, R. Jeewon, G. Zengin, et al. Crit Rev Food Sci Nutr. 59, sup1: S210-S43 (2019) [CrossRef] [PubMed] [Google Scholar]
S. Singh, I. Kapoor, G. Singh, C. Schuff, M. Lampasona, C. Catalan. Chemistry, Antioxidant and Antimicrobial Potentials of White Pepper (Piper nigrum L.) Essential Oil and Oleoresins. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences. 83, 3 (2013) [Google Scholar]
Z. Zarai, E. Boujelbene, N. Ben Salem, Y. Gargouri, A. Sayari. Antioxidant and antimicrobial activities of various solvent extracts, piperine and piperic acid from Piper nigrum. LWT. 50, 2:634-41 (2013) [Google Scholar]
M. Quraishi, D. Kumar, I. Ahamad. Corrosion. 2, 56-60 (2009) [Google Scholar]
P. BrahmaNaidu, H. Nemani, B. Meriga, S.K. Mehar, S. Potana, S. Ramgopalrao. Chem Biol Interact. 221, 42-51 (2014) [CrossRef] [PubMed] [Google Scholar]
S.A. Sudjarwo, K. Eraiko, G.W. Sudjarwo, Koerniasari. Iran J Basic Med Sci. 20, 11:1227-31 (2017) [PubMed] [Google Scholar]
A. Manayi, S.M. Nabavi, W.N. Setzer, S. Jafari. Curr Med Chem. 25, 37:4918-28 (2018) [Google Scholar]
Z. Stojanović-Radić, M. Pejčić, M. Dimitrijević, A. Aleksić, N. V. Anil Kumar, B. Salehi, et al. Appl. Sci. 9, 20:4270 (2019) [CrossRef] [Google Scholar]
N. Septiyorini, S. Purwono, D.M. Rizal. The Effect of Black Pepper Fruits (Piper nigrum L.) on the Increase of Erection. Proceedings of the 1^st International Conference on Community Health (ICCH 2019), 2020/02/10: Atlantis Press (2020) [Google Scholar]
S. Kumar, S. Murugeasn, B. Raja. Int. J. Pharm. Sci. Res. 1, 300-7 (2010) [Google Scholar]
S. Kumar, S. Malhotra, A.K. Prasad, E.V. Van der Eycken, M.E. Bracke, W.G. Stetler-Stevenson, et al. Curr Top Med Chem. 15, 9:886-93 (2015) [CrossRef] [PubMed] [Google Scholar]
S. Kumar, V. Singhal, R. Roshan, A. Sharma, G.W. Rembhotkar, B. Ghosh. Eur J Pharmacol. 575, 1-3:177-86 (2007) [CrossRef] [PubMed] [Google Scholar]
K. Tkachenko, M. Frontasyeva, A. Vasilev, L. Avramov, L. Shi. Plants (Basel). 9, 12:1764 (2020) [CrossRef] [Google Scholar]
P. Ercan, S.N. El. Food Chem. 205:163-9 (2016) [CrossRef] [PubMed] [Google Scholar]
S. Zhang, H. Li, H. Xu, S.J. Yang. Yao Xue Xue Bao. 45, 1:31-6 (2010) [PubMed] [Google Scholar]
F. Zhai, H. Li, F. Zhou, F. Lin, L. Guan. Med Recapitulate. 21, 24:4539-40 (2015) [Google Scholar]
T.E. Goranova, S.S. Bozhanov, V.S. Lozanov, V.I. Mitev, R.P. Kaneva, E.I. Georgieva. Neoplasma.62, 1:27-33 (2015) [CrossRef] [PubMed] [Google Scholar]
R. Ștefănescu, A. Tero-Vescan, A. Negroiu, E. Aurică, C.E. Vari. Biomolecules. 10, 5 (2020) [Google Scholar]
D. Dinchev, B. Janda, L. Evstatieva, W. Oleszek, M.R. Aslani, I. Kostova. Phytochemistry. 69, 1:176-86 (2008) [CrossRef] [PubMed] [Google Scholar]
M. Shishovska, Z. Arsova-Sarafinovska, S. Memeti. J. chem. eng. res. updates. 2, 12-21 (2015) [CrossRef] [Google Scholar]
S.C. Kam, J.M. Do, J.H. Choi, B.T. Jeon, G.S. Roh, J.S. Hyun. J Sex Med. 9, 10:2544-51 (2012) [CrossRef] [PubMed] [Google Scholar]
J. Do, S. Choi, J. Choi, J.S. Hyun. Korean J Urol. 54, 3:183-8 (2013) [CrossRef] [PubMed] [Google Scholar]
H. Zhang, W.T Tong, C.R. Zhang, J.L. Li, H. Meng, H.G. Yang, et al. Diabetes Metab Syndr Obes. 12, 1705-16 (2019) [CrossRef] [Google Scholar]
R. Bhat, A.A. Karim. Fitoterapia. 81, 7:669-79 (2010) [CrossRef] [PubMed] [Google Scholar]
S. Hussein, R. Ibrahim, K. LingPick. J. Trop. Med. Plants. 8, 1:103-10 (2007) [Google Scholar]
M.A. Hassali, T. Khan, A. Shafie, N. Munaver. Aust. J. Med. Sci. 1 (2009) [Google Scholar]
S.M. Ezzat, M.M. Okba, M.I. Ezzat, N.M. Aborehab, S.O. Mohamed. Evid Based Complement Alternat Med. 2019 (2019) [Google Scholar]
K.L. Tong, K.L. Chan, S. AbuBakar, B.S. Low, H.Q. Ma, P.F. Wong. PLoS One. 10, 3:e0121752-e (2015) [CrossRef] [PubMed] [Google Scholar]
M. Chen, R. Chen, W. Shengpeng, Z. Tan, Y. Hu, X. Peng, et al. Int J Nanomedicine. 8, 85-92 (2013) [CrossRef] [PubMed] [Google Scholar]
F.B.M. Priviero, L.M. Jin, Z. Ying, C.E. Teixeira, R.C. J Pharmacol Exp Ther. 333, 1:184-92 (2010) [CrossRef] [PubMed] [Google Scholar]
P. Hedlund, A. Aszódi, A. Pfeifer, P. Alm, F. Hofmann, M. Ahmad, et al. Erectile dysfunction in cyclic GMP-dependent kinase I-deficient mice. Proceedings of the National Academy of Sciences. 97, 5:2349-54 (2000) [CrossRef] [PubMed] [Google Scholar]
A.J. Becker, S. Uckert, C.G. Stief, M.C. Truss, S. Machtens, F. Scheller, et al. Urology. 57, 1:193-8 (2001) [CrossRef] [PubMed] [Google Scholar]
B.H. Tee, S.Z. Hoe, S.H. Cheah, S.K. Lam. Med Princ Pract. 26, 3:258-65 (2017) [CrossRef] [PubMed] [Google Scholar]
R.C. Dean, T.F. Lue. Urol Clin North Am. 32, 4:379-v (2005) [CrossRef] [PubMed] [Google Scholar]

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