Evaluation of the Effect of a New Fully Biodegradable External Dressing for Promoting Diabetic Ulcerative Wound Healing

Open Access

Issue		BIO Web Conf. Volume 111, 2024 2024 6^th International Conference on Biotechnology and Biomedicine (ICBB 2024)


Article Number		02001
Number of page(s)		7
Section		Biomedical Advances and Personalized Medicine
DOI		https://doi.org/10.1051/bioconf/202411102001
Published online		31 May 2024

S. Dhivya, V. V. Padma, and E. Santhini, “Wound dressings - a review,” BioMed, vol. 5, no. 4, p. 22, Dec. 2015. [CrossRef] [Google Scholar]
V. R. Güiza-Argüello, V. A. Solarte-David, A. V. Pinzón-Mora, J.E. Ávila-Quiroga, and S.M. Becerra-Bayona, “Current advances in the development of hydrogel-based wound dressings for diabetic foot ulcer treatment,” Polymers, vol. 14, no. 14, p. 2764, Jul. 2022. [CrossRef] [PubMed] [Google Scholar]
O. Wichterle, D. Lim, “Hydrophilic gels for biological use,” Nature, vol. 185, no. 4706, pp. 117–118, Jan. 1960. [CrossRef] [Google Scholar]
G. D. Winter, “Formation of the scab and the rate of epithelization of superficial wounds in the skin of the young domestic pig,” Nature, vol. 193, no. 4812, pp. 293–294, Jan. 1962. [CrossRef] [PubMed] [Google Scholar]
P. B. Kajjari, L. S. Manjeshwar, and T. M. Aminabhavi, “Novel pH- and temperature-responsive blend hydrogel microspheres of sodium alginate and PNIPAAm-g-GG for controlled release of isoniazid,” Aaps. Pharmscitech., vol. 13, no. 4, pp. 1147–1157, Dec. 2012. [CrossRef] [Google Scholar]
Y. Wei, J. Chen, S. Yu, M. Zhang, M. Liao, and Q. Dai, “Study on the synthesis and sctivity of four rn-conotoxins,” Chin. J. Mar. Drugs., vol. 41, no. 3, pp. 17–24, 2022. [Google Scholar]
M. Zhou, M. Yang, H. Wen, S. Xu, C. Han, and Y. Wu, “O1-conotoxin Tx6.7 cloned from the genomic DNA of Conus textile that inhibits calcium currents,” J. Venom. Anim. Toxins incl. Trop. Dis, vol. 29, p. e20220085, 2023. [CrossRef] [Google Scholar]
L.-T. Lim, R. Auras, and M. Rubino, “Processing technologies for poly(lactic acid),” Prog. Polym. Sci., vol. 33, no. 8, pp. 820–852, Aug. 2008. [CrossRef] [Google Scholar]
S. Li, S. Yang, and D. Xu, “Preparation and application of biodegradable material polylactic acid,” Chem. Manage., no. 5, pp. 69-71, 2023. [Google Scholar]
J. B. Cole and J. C. Florez, “Genetics of diabetes mellitus and diabetes complications,” Nat. Rev. Nephrol., vol. 16, no. 7, pp. 377–390, Jul. 2020,. [CrossRef] [PubMed] [Google Scholar]
Y. Zheng, S. H. Ley, and F. B. Hu, “Global aetiology and epidemiology of type 2 diabetes mellitus and its complications,” Nat. Rev. Endocrinol., vol. 14, no. 2, pp. 88–98, Feb. 2018. [CrossRef] [PubMed] [Google Scholar]
A. V. A. Mariadoss, A. S. Sivakumar, C.-H. Lee, and S. J. Kim, “Diabetes mellitus and diabetic foot ulcer: Etiology, biochemical and molecular based treatment strategies via gene and nanotherapy,” Biomed. Pharmacother., vol. 151, p. 113134, Jul. 2022. [CrossRef] [Google Scholar]
E. Everett and N. Mathioudakis, “Update on management of diabetic foot ulcers: Diabetic foot ulcers,” Ann. N.Y. Acad. Sci., vol. 1411, no. 1, pp. 153–165, Jan. 2018. [CrossRef] [PubMed] [Google Scholar]
International Diabetes Federation (IDF). IDF DIABETES ATLAS. 10th Edition 2021. [Google Scholar]
Y. Wang et al., “An update on potential biomarkers for diagnosing diabetic foot ulcer at early stage,” Biomed. Pharmacother., vol. 133, p. 110991, Jan. 2021. [CrossRef] [Google Scholar]
H. Wu et al., “The promising hydrogel candidates for preclinically treating diabetic foot ulcer: a systematic review and meta-analysis,” Adv. Wound. Care., vol. 12, no. 1, pp. 28–37, Jan. 2023. [CrossRef] [PubMed] [Google Scholar]
V. Jones, J. E. Grey, K. G. Harding, “Wound dressings,” Bmj, vol. 332, no. 7544, pp. 777–780, Apr. 2006. [CrossRef] [PubMed] [Google Scholar]
M. Farahani and A. Shafiee, “Wound healing: from passive to smart dressings,” Adv. Healthc. Mater., vol. 10, no. 16, p. 2100477, Aug. 2021. [Google Scholar]
D. Song, L. Wei, R. Sun, Y. Zhang, and Z. Zhang, “Research progress of alginate fiber in biomedical field,” Cotton. Text. Technol., vol. 49, no. 4, pp. 74–79, 2021. [Google Scholar]
J. Qin, M. Sui, B. Yuan, J. Wang, Z. Yuan, and G. Xu, “The behavior and effects of silver nanoparticles in the aquatic environment,” Sichuan. Environ., vol. 36, no. 6, pp. 155–160, 2017. [Google Scholar]
C. J. L. Murray et al., “Five insights from the Global Burden of Disease Study 2019,” Lancet, vol. 396, no. 10258, pp. 1135–1159, Oct. 2020. [CrossRef] [PubMed] [Google Scholar]
Q. Han et al., “Effect of Zizhu Ointment on inflammatory response and NF-kB/JNK/PI3K signal expression of diabetic foot ulcer infected by staphylococcus aureus,” J. Tianjin Univ. Tradit. Chin. Med., vol. 4, no. 2, pp. 226–234, 2021. [Google Scholar]
J. Z. M. Lim, N. S. L. Ng, and C. Thomas, “Prevention and treatment of diabetic foot ulcers,” J. Roy. Soc. Med., vol. 110, no. 3, pp. 104–109, Mar. 2017. [CrossRef] [PubMed] [Google Scholar]
X. Wang, G. Liu, and L. Xu, “Advances in the efficacy and safety of nano-silver dressings for diabetic foot ulcers(DFU)healing,” J. Hainan Med. Univ., vol. 29, no. 9, pp. 715–720, 2023. [Google Scholar]
L. Xu, Y.-Y. Wang, J. Huang, C.-Y. Chen, Z.-X. Wang, and H. Xie, “Silver nanoparticles: Synthesis, medical applications and biosafety,” Theranostics, vol. 10, no. 20, pp. 8996–9031, 2020. [CrossRef] [PubMed] [Google Scholar]
E. McGillicuddy et al., “Silver nanoparticles in the environment: Sources, detection and ecotoxicology,” Sci. Total. Environ., vol. 575, pp. 231–246, Jan. 2017. [CrossRef] [Google Scholar]
J. Wang, “Application of Natural Polymer Biomaterials in New Medical Dressings,” Plast. Addit., vol. 04, pp. 52–55 +71, Aug. 2021. [Google Scholar]
Q. Liu, Z. Wang, and X. Yu, “Classification and Research Progress on the Natural Polymer-Based HydrogelsClassification and Research Progress on the Natural Polymer-Based Hydrogels,” Henan. Sci. Technol., vol. 42, no. 02, pp. 93–96, Jan. 2023. [Google Scholar]
H. Korting, C. Schöllmann, and R. White, “Management of minor acute cutaneous wounds: importance of wound healing in a moist environment: Acute wounds and healing,” J. Eur. Acad. Dermatol., vol. 25, no. 2, pp. 130–137, Feb. 2011. [CrossRef] [PubMed] [Google Scholar]
D. Li, J. Li, J. Yu, J. Cheng, J. Qiang, “Research Status of Self-healing Hydrogel Wound Dressing,” Guangdong Chem. Ind., vol. 48, no. 01, pp. 54–56, Jan. 2021. [Google Scholar]
Y. Ma, “Preparation and application of biodegradable hydrogelwound dressing for medical care,” Adhesion, vol. 49, no. 08, pp. 13–16, Aug. 2022. [Google Scholar]
J. Zhun, “Research Progress of Multifunctional Polymer Antibacterial Hydrogel in Wound Dressing,” Shanxi Chem. Ind., vol. 43, no. 3, pp. 45–47, Mar. 2023. [Google Scholar]
X. Wang, et al., “Scarless Wound Healing: Current Insights from the Perspectives of TGF-ß, KGF-1, and KGF-2,” Cytokine. Growth. F. R., vol. 66, pp. 26–37, Aug. 2022. [CrossRef] [Google Scholar]
S. A. Shah, M. Sohail, S. A. Khan, and M. Kousar, “Improved drug delivery and accelerated diabetic wound healing by chondroitin sulfate grafted alginate-based thermoreversible hydrogels,” Mat. Sci. Eng. C-mater., vol. 126, p. 112169, Jul. 2021. [CrossRef] [Google Scholar]
F. Sun, “Research and Development of Biodegradable Polymer Materials,” Chin. Petrol. Chem. Stand. Qual., vol. 41, no. 02, pp. 124–126, 2021. [Google Scholar]
R. Wang, et al., “Recent Application Advances of Biodegradable Polymeric Materials,” Shandong Chem. Ind., vol. 51, no. 05, pp. 98–99+103, 2022. [Google Scholar]
R. Cui et al., “Polysaccharide-Based hydrogels for wound dressing: design considerations and clinical applications,” Front. Bioeng. Biotech., vol. 10, p. 845735, Mar. 2022. [CrossRef] [Google Scholar]
H. N. Wilkinson and M. J. Hardman, “Wound healing: cellular mechanisms and pathological outcomes,” Open Biol., vol. 10, no. 9, p. 200223, Sep. 2020. [CrossRef] [Google Scholar]
R. Zhang, Y. Wang, B. Zhang, Y. Guo, “A hydrogel dressing used to repair skin wounds,” Sci. Technol. Gelatin., vol. 42, no. 2, pp. 68–79, Jun. 2022. [Google Scholar]
Y. Liang, J. He, B. Guo, “Functional hydrogels as wound dressing to enhance wound healing,” Acs Nano, vol. 15, no. 8, pp. 12687–12722, Aug. 2021. [CrossRef] [PubMed] [Google Scholar]
M. Zhang and X. Zhao, “Alginate hydrogel dressings for advanced wound management,” Int. J. of Bio.l Macromol., vol. 162, pp. 1414–1428, Nov. 2020. [CrossRef] [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.