Open Access
Issue
BIO Web Conf.
Volume 157, 2025
The 5th Sustainability and Resilience of Coastal Management (SRCM 2024)
Article Number 05010
Number of page(s) 7
Section Environmental Monitoring and Sustainability
DOI https://doi.org/10.1051/bioconf/202515705010
Published online 05 February 2025
  • Sung H, Ferlay J, Siegel R L, Laversanne M, Soerjomataram I, Jemal A and Bray F 2021 Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin. 71 pp 209-49 [CrossRef] [PubMed] [Google Scholar]
  • Ibrahim S, Putra A, Amalina N D and Nasution I P A 2022 Heat shock protein-70 expression in CSCs tumor-associated macrophages induced by Typhonium flagelliforme tuber extract Journal of Applied Pharmaceutical Science 12 pp 146-52 [CrossRef] [Google Scholar]
  • Yadav A K and Desai N S 2019 Cancer stem cells: acquisition, characteristics, therapeutic implications, targeting strategies and future prospects Stem Cell Rev Rep. 15 pp 331-55 [CrossRef] [Google Scholar]
  • Hermansyah D, Putra A, Munir D, Lelo A, Amalina N D and Alif I 2021 Synergistic effect of Curcuma longa extract in combination with Phyllanthus niruri extract in regulating annexin A2, epidermal growth factor receptor, matrix metalloproteinases, and pyruvate kinase M1/2 signaling pathway on breast cancer stem cell Open Access Maced J Med Sci. 9 pp 271–85 [CrossRef] [Google Scholar]
  • Alanazi I O and Khan Z 2016 Understanding EGFR signaling in breast cancer and breast cancer stem cells: overexpression and therapeutic implications. Asian Pac J Cancer Prev. 17 pp 445-53 [CrossRef] [PubMed] [Google Scholar]
  • Zhao L, Qiu T, Jiang D, Xu H, Zou L, Yang Q, Chen C and Jiao B 2020 SGCE promotes breast cancer stem cells by stabilizing EGFR Advanced Science 7 pp 1-17 [Google Scholar]
  • Flynn J F Wong C and Wu J M 2009 Anti-EGFR therapy: mechanism and advances in clinical efficacy in breast cancer J Oncol. pp 1-16 [Google Scholar]
  • Sritharan S and Sivalingam N 2021 A comprehensive review on time-tested anticancer drug doxorubicin Life Sciences 278 pp 1-10 [Google Scholar]
  • Varela-López A, Battino M, Navarro-Horta M D, Giampieri F, Forbes-Hernández T Y, Romero-Márquez J M, Collado R, Quiles J L 2019 An update on the mechanisms related to cell death and toxicity of doxorubicin and the protective role of nutrients Food and Chemical Toxicology 134 pp 1-19 [Google Scholar]
  • Shady N H, El-Hossary E M, Fouad M A, Gulder T A M, Kamel M S and Abdelmohsen U R 2017 Bioactive natural products of marine sponges from the genus Hyrtios Molecules 22 pp 1-21 [Google Scholar]
  • Wati F A, Santoso M, Moussa Z, Fatmawati S, Fadlan A and Judeh Z M A 2021 Chemistry of trisindolines: natural occurrence, synthesis and bioactivity RSC Advances 11 pp 25381-421 [CrossRef] [PubMed] [Google Scholar]
  • Kobayashi M, Aoki S, Gato K, Matsunami K, Kurosu M and Kitagawa I 1994 Marine Naural Products. XXXIV.1) trisindoline, a new antibiotic indole trimer, produced by a bacterium of Vibrio sp. Separated from the marine sponge Hyrtios altum Chem. Pharm. Bull. 42 pp 2449-51 [CrossRef] [PubMed] [Google Scholar]
  • Nurhayati A P D, Rihandoko A, Fadlan A, Ghaissani S S, Jadid N and Setiawan E 2022 Anti-cancer potency by induced apoptosis by molecular docking P53, caspase, cyclin D1, cytotoxicity analysis and phagocytosis activity of trisindoline 1, 3 and 4. Saudi Pharmaceutical Journal, in press [Google Scholar]
  • Ghaissani S S 2022 Study of trisindoline 1 compound exposure in P53 and P53R2 gene expression of cancer stem cell (CSC) Master thesis Institut Teknologi Sepuluh Nopember, Biology Department [Google Scholar]
  • Wati F A (2021) Development of nitrogen heterocyclic compunds as antituberculosis and anticancer. Doctoral thesis Institut Teknologi Sepuluh Nopember, Chemistry Department [Google Scholar]
  • Al-Anazi M, Khairuddean M, Al-Najjar B O, Alidmat M M, Kamal N N S N M and Muhamad M 2022 Synthesis, anticancer activity and docking studies of pyrazoline and pyrimidine derivates as potential epidermal growth factor receptor (EGFR) inhibitors Arabian Journal of Chemistry 15 pp 1-10 [Google Scholar]
  • Freire E 2008 Do enthalpy and entropy distinguish first in class from best in class? Drug Discov Today 13 pp 869–74 [CrossRef] [PubMed] [Google Scholar]
  • Pantsar T and Poso A 2018 Binding affinity via docking: fact and fiction Molecules 23 pp 1-11 [Google Scholar]
  • Kastritis P L and Bonvin A M J J 2013 On the binding affinity of macromolecular interactions: daring to ask why proteins interact J R Soc Interface 10 pp 1-27 [Google Scholar]
  • Santos K B, Guedes I A, Karl A L M and Dardenne L E 2020 Highly flexible ligand docking: benchmarking of the DockThor program on the LEADS-PEP protein-peptide data set Journal of Chemical Information and Modeling 60 pp 667-83 [CrossRef] [PubMed] [Google Scholar]
  • Ciardiello F and Tortora G 2008 EGFR antagonists in cancer treatment New England Journal of Medicine 358 pp 1160-74 [CrossRef] [PubMed] [Google Scholar]
  • Calderon O H, Pérez A F Y, Saumeth J Q, Armas J P R, Pacheco M P, Sánchez J M O, Macedo E C C, Acevedo J L A, Salvador L F, Rojas G P and Ayme V A 2020 Carvacrol: an in silico approach of a candidate drug on HER2, PI3Kα, mTOR, hER-α, PR and EGFR receptors in the breast cancer Evidence-Based Complementary and Alternative Medicine 8830665 pp 1-12 [Google Scholar]
  • Wu MY, Dai DQ and Yan H 2012 PRL-Dock: protein-ligand docking based on hydrogen bond matching and probabilistic relaxation labeling Proteins: Structure, Function, and Bioinformatics 80 pp 2137-53 [CrossRef] [PubMed] [Google Scholar]
  • Pace C N, Fu H, Fryar K L, Landua J, Trevino S R, Schell D, Thurlkill R L, Imura S, Scholtz J M, Gajiwala K, Sevcik J, Urbanikova L, Myers J K, Takano K, Hebert E J, Shirley B A and Grimsley G R 2014 Contribution of hydrogen bonds to protein stability Protein Sci. 23 pp 652-61 [CrossRef] [PubMed] [Google Scholar]
  • Liao Q H, Gao Q Z, Wei J and Chou K C 2011 Docking and molecular dynamics study on the inhibitory activity of novel inhibitors on epidermal growth factor receptor (EGFR) Medicinal Chemistry 7 pp 24-31 [CrossRef] [Google Scholar]
  • Ono M and Kuwano M 2006 Molecular mechanisms of epidermal growth factor receptor (EGFR) activation and response to gefitinib and other EGFR-targeting drugs Clin Cancer Res 12 pp 7242-51 [CrossRef] [PubMed] [Google Scholar]
  • Masuda H, Zhang D, Bartholomeusz C, Doihara H, Hortobagyi G N and Ueno N T 2012 Role of epidermal growth factor receptor in breast cancer Breast Cancer Res Treat. 136 pp 1-21 [Google Scholar]
  • Paramanantham A, Jung E J, Kim H J, Jeong B K, Jung J M, Kim G S, Chan H S and Lee W S 2021 Doxorubicin-resistant TNBC cells exhibit rapid growth with cancer stem cell-like properties and EMT phenotype, which can be transferred to parental cells through autocrine signaling Int. J. Mol. Sci. 22 pp 1-14 [Google Scholar]
  • Abhold E L, Kiang A, Rahimy E, Kuo S Z, Rodriguez J W, Lopez J P, Blair K J, Yu M A, Haas M, Brumund K T, Altuna X, Patel A, Weisman R A and Ongkeko W M 2012 EGFR kinase promotes acquisition of stem cell-like properties: a potential therapeutic target in head and neck squamous cell carcinoma stem cells PLoS ONE 7 pp 1-8 [Google Scholar]

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