Eco-Friendly strategy to Control Soil-Borne Phytopathogens Macrophomina phaseolina and Fusarium oxysporum, Employing Synergistic PhytoMycoBiological Combination

Open Access

Issue		BIO Web Conf. Volume 233, 2026 9^th International Conference on Advances in Biosciences and Biotechnology: Emerging Innovations in Biomedical and Bioengineering Sciences (ICABB 2026)


Article Number		02010
Number of page(s)		13
Section		Environmental Biotechnology and Sustainable Agriculture
DOI		https://doi.org/10.1051/bioconf/202623302010
Published online		23 April 2026

Chandini A, Prasad RD, Sakthivel K, Duraimurugan P, Chandrika KSVP, Sarada Ch, et al. In vitro Evaluation of Trichoderma harzianum (Th4d) for the Management of Foliar and Soil Borne Pathogens of Castor. Journal of Advances in Biology & Biotechnology. 2025, 28(6):588–99. https://doi.org/10.9734/iabb/2025/v28i62423 [Google Scholar]
Abomughaid MM, Teibo JO, Akinfe OA, Adewolu AM, Teibo TKA, Afifi M, et al. A phytochemical and pharmacological review of Ricinus communis L. Discover Applied Sciences. 2024, 6(6). https://doi.org/10.1007/s42452-024-05964-5 [Google Scholar]
Ramothloa TP, Mkolo NM, Motshudi MC, Mphephu MM, Makhafola MA, Naidoo CM. Phytochemical Composition and Multifunctional Applications of Ricinus communis L.: Insights into Therapeutic, Pharmacological, and Industrial Potential. Molecules. 2025,30(15):3214. https://doi.org/10.3390/molecules30153214 [Google Scholar]
Nofal AM, Hamouda RA, Rizk A, El-Rahman MA, Takla AK, Galal H, et al. Polyphenols-Rich Extract of Calotropis procera Alone and in Combination with Trichoderma Culture Filtrate for Biocontrol of Cantaloupe Wilt and Root Rot Fungi. Molecules. 2023, 29(1): 139. https://d0i.0rg/l0.3390/molecules29010139 [Google Scholar]
Wang J, Mu H, Liu S, Qi S, Mou S. Effects of Trichoderma harzianum on Growth and Rhizosphere Microbial Community of Continuous Cropping Lagenaria siceraria. Microorganisms . 2024 12(10): 1987. https://doi.org/10.3390/microorganismsl2101987 [Google Scholar]
Jambhulkar PP, Singh B, Raja M, Ismaiel A, Lakshman DK, Tomar M, et al. Genetic diversity and antagonistic properties of Trichoderma strains from the crop rhizospheres in southern Rajasthan, India. Scientific Reports. 2024, 14(l):8610. https://doi.org/10.1038/s41598-024-583Q2-5 [Google Scholar]
Achaiya D, Parida P, Mohapatra HS, Mallik S, Mohanty JN, Sahoo SL. Phytochemical analysis and evaluation of inhibitory potential of Ricinus communis leaf extract against novel Bacillus pathogens. Beni-Suef University Journal of Basic and Applied Sciences . 2025, 14(1). https://doi.org/10.1186/s43088-025-0Q666-2 [Google Scholar]
Akbar R, Manzoor S, Azad R, Makai G, Rahim J, Sheikh UAA, et al. Botanical Pesticides: Role of Ricinus communis in Managing Bactrocera zonata (Tephritidae: Diptera). Insects. 2024, 15(12):959. https://doi.org/10.3390/insectsl512Q959 [Google Scholar]
Endris YA, Abdu KY, Abate SG. Investigation of bioactive phytochemical compounds of the Ethiopian medicinal plant using GC-MS and FTIR. Heliyon. 2024, 10(15):e34687. https://d0i.0rg/l0.1016/j.heliyon.2024.e34687 [Google Scholar]
Ding H, Li X, Wang S, Yang Y, Chen X, Chen C, et al. Trichoderma harzianum for the control of agricultural pests: Potential, progress, applications and future prospects. Revista Argentina De Microbiologfa 2025 , https://doi.Org/10.1016/j.ram.2025.09.004 [Google Scholar]
Kumari R, Kumar V, Arukha AP, Rabbee MF, Ameen F, Koul B. Screening of the Biocontrol Efficacy of Potent Trichoderma Strains against Fusarium oxysporum f.sp. ciceri and Scelrotium rolfsii Causing Wilt and Collar Rot in Chickpea. Microorganisms.2024,12(7):1280.https://doi.org/10.3390/microorganismsl2071280 [Google Scholar]
Arya AK, Kumar G, Singh V, Afaq N, Shukla S, Singh S, et al. Unveiling the Antimicrobial Potential of Ricinus communis'. A Comprehensive Review of Its Relevance to Surgical Site Infection (SSI) Pathogens. Cureus . 2025,17(12). https://doi.org/10.7759/cureus.99803 [Google Scholar]
Naz R, Bano A. Antimicrobial potential of Ricinus communis leaf extracts in different solvents against pathogenic bacterial and fungal strains. Asian Pacific Journal of Tropical Biomedicine .2012,2(12):944–7. https://doi.org/10.1016/s2221-1691(13)60004-0 [Google Scholar]
Singh NK, Khatiwada N. Calotropis procera plant extract: phytochemical analysis, antimicrobial activity, and coumarin compound identification. KMC Journal. 2025, 7(1):371—88. https://doi.org/10.3126/kmcj.v7il.75161 [Google Scholar]
Rodriguez-Macias JD, Saurith-Coronell O, Parra LM, Carrascal-Hemandez DC, Fuentes-Gandara F, Insuasty D, et al. Integrated In Vitro and In Silico Evaluation of the Antimicrobial and Cytotoxic Potential of Calotropis procera Leaf Ethanolic Extract: From GC-MS Profiling to Molecular Docking and Dynamics. International Journal of Molecular Sciences. 2025, 26(21): 10574. https://doi.org/10.3390/ijms262110574 [Google Scholar]
Kredics L, Buchner R, Balazs D, Allaga H, Kedves O, Racic G, et al. Recent advances in the use of Tr/cAocferma-containing multicomponent microbial inoculants for pathogen control and plant growth promotion. World Journal of Microbiology and Biotechnology 2024,40(5): 162. https://doi.org/10.1007/sll274-024-Q3965-5 [Google Scholar]
Mitrovic I, Canak P, Zivanov ST, Farkas H, Vasiljevic M, Cujic S, et al. Trichoderma harzianum in Biocontrol of Maize Fungal Diseases and Relevant Mycotoxins: From the Laboratory to the Field. Journal of Fungi 11(6):416. https://doi.org/10.3390/jofll060416 [Google Scholar]
Wang X, Zhao Z, Li H, Wei Y, Hu J, Yang H, et al. The growth-promoting and disease-suppressing mechanisms of Trichoderma inoculation on peanut seedlings. Frontiers in Plant Science 2024,15:1414193. https://doi.org/10.3389/fpls.2024.1414193 [Google Scholar]
Guzman-Guzman P, Etesami H, Santoyo G. Trichoderma’. a multifunctional agent in plant health and microbiome interactions. BMC Microbiology 2025 Jul 12;25(1):434. https://doi.org/10.1186/sl2866-025-04158-2 [Google Scholar]
Morsy N, Sherif E a. A, Abdel-Rassol TMA. Phytochemical analysis of Calotropis procera with antimicrobial activity investigation. Main Group Chemistry. 2016,15(3):267–73 https://doi.Org/l0.3233/mgc-160206 [Google Scholar]
Ramothloa TP, Mkolo NM, Motshudi MC, Mphephu MM, Makhafola MA, Naidoo CM. Phytochemical Composition and Multifunctional Applications of Ricinus communis L:. Insights into Therapeutic, Pharmacological, and Industrial Potential. Molecules. 2025, 30(15):3214. https://doi.org/10.3390/molecules30153214 [Google Scholar]
Veeramani P, Subrahmaniyan K, Harisudan C, Vijayan R, Saravanan PA, Velmurugan M, et al. Exploring the medicinal potential of Castor {Ricinus communis L.): A comprehensive review. Annals of Phytomedicine an International Journal 2024,13(2). https://doi.Org/10.54085/ap.2024.13.2.19 [Google Scholar]
Kundu S. A mini review on Calotropis procera and tapping its phytochemical and pharmacological potential. The Journal of Phytopharmacology . 2021,10(4):277–80. https://doi.org/10.31254/phvto.2021.10411 [Google Scholar]
Kaur A, Batish DR, Kaur S, Chauhan BS. An Overview of the Characteristics and Potential of Calotropis procera From Botanical, Ecological, and Economic Perspectives. Frontiers in Plant Science 2021,12:690806. https://doi.org/10.3389/fpls.2021.690806 [Google Scholar]
Abew B, Sahile S, Moges F. In vitro antibacterial activity of leaf extracts of Zehneria scabra and Ricinus communis against Escherichia coli and methicillin resistance Staphylococcus aureus. Asian Pacific Journal of Tropical Biomedicine. 2014, 4(10):816–20. https://doi.Org/10.12980/apitb.4.201414bl6 [Google Scholar]
Abbas A, Mubeen M, Zheng H, Sohail MA, Shakeel Q, Solanki MK, et al. Trichoderma spp. Genes Involved in the Biocontrol Activity Against Rhizoctonia solani. Frontiers in Microbiology. 2022, 13:884469.https://doi.org/10.3389/finicb.2022.884469 [Google Scholar]
Landoni M, Bertagnon G, Ghidoli M, Cassani E, Adani F, Pilu R. Opportunities and Challenges of Castor Bean (Ricinus communis L.) Genetic Improvement. Agronomy . 2023,13(8):2076. https://doi.org/10.3390/agronomyl3082076 [Google Scholar]
Ahmed F. Antioxidant activity of Ricinus Communis. Organic and Medicinal Chemistry International Journal. 2018, 5(4).https://doi.org/10.19080/omcii.2018.05.555667 [Google Scholar]
Zarai Z, Chobba IB, Mansour RB, Bekir A, Gharsallah N, Kadri A. Essential oil of the leaves of Ricinus communis L.: In vitro cytotoxicity and antimicrobial properties. Lipids in Health and Disease 2012,11(1):102. https://www.lipidworld.eom/content/l1/1/102 [Google Scholar]
Foster JT, Allan GJ, Chan AP, Rabinowicz PD, Ravel J, Jackson PJ, et al. Single nucleotide polymorphisms for assessing genetic diversity in castor bean (Ricinus communis). BMC Plant Biology 2010,10(l):13. http://www.biomedcentral.com/1471-2229/10/13 [Google Scholar]

Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.

Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.

Initial download of the metrics may take a while.