BIO Web of Conferences
Volume 3, 201437th World Congress of Vine and Wine and 12th General Assembly of the OIV (Part 1)
|Number of page(s)||4|
|Section||Safety and Health|
|Published online||04 November 2014|
Development of an in vitro model to simulate the gastrointestinal digestion and absorption of stabilizing agents
Dipartimento di Scienze Farmacologiche e Biomolecolari, Università degli Studi di Milano, 20133 Milano, Italy
Each step in the winemaking process must be carefully planned and controlled to optimize the quality of wine. Among others, tartaric stabilization is a critical step in enology, and although effective, the usual practices to solve it show some qualitative limitations, and important economical and environmental impacts. For the reasons reported above, the wine producers are searching for alternative practices, with particular interest in the area of organic products. Biopolymers are possible alternatives in this field. The selection, the characterization and the safety aspects of new biopolymers are the objectives of the European project STABIWINE (Use of biopolymers for sustainable stabilization of quality wines). The first group of biopolymers analyzed includes polyaminoacids and, in particular, polymers of L-aspartic acid (PAA), which can be used as enological additives for tartaric stabilization. In order to contribute in drafting the toxicological dossier, the metabolic fate of PAAs has been assessed by in vitro models, mimicking gastrointestinal digestion and absorption.
© Owned by the authors, published by EDP Sciences, 2014
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.