| Issue |
BIO Web Conf.
Volume 8, 2017
2016 International Conference on Medicine Sciences and Bioengineering (ICMSB2016)
|
|
|---|---|---|
| Article Number | 01024 | |
| Number of page(s) | 6 | |
| Section | Session I: Medicine | |
| DOI | https://doi.org/10.1051/bioconf/20170801024 | |
| Published online | 11 January 2017 | |
Comparison of clinical efficacy between decitabine combined with half the amount of CAG regimen with CAG regimen alone in patients with inermediate to high-risk myelodysplastic syndrome
1 College Nursing of Beihua University, 132000, jilin city, jilin province, China
2 Hematology of Affiliated Hospital of Beihua University, 132000, jilin city, jilin province, China
a Corresponding author: Zhenwei Fan: 22289671@qq.com
Objective: To investigate the efficacy and safety of decitabine combined with half the amount of CAG and CAG regimen alone. Methods: Comparison the effectiveness, overall survival and incidence of adverse reactions of 42 cases of MDS used decitabine combined with half the amount of CAG regimen (decitabine 20mg/m2, once a day, d1-3, Accra neomycin 7mg/m2,intravenous injection, once a day, d4-7, cytarabine 10mg/m2, every 12 hours, d4-10, granulocyte colony stimulating factor 300μg, once a day, d4-10, white blood cell count>20×109/L when deactivated for four courses) and 48 patients in MDS were treated with chemotherapy alone CAG (Accra neomycin 14mg/m2,once a day, d1-3, cytarabine 10mg/m2, every 12 hours, d1-14, granulocyte colony stimulating factor 300μg, once a day, d1-14, white blood cell count>20×109/L when deactivated). Results: Compared with pure CAG, clinical efficacy of decitabine combined with half the amount of CAG regimen is better, the treatment does not increase the risk.
© The Authors, published by EDP Sciences, 2017
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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