| Issue |
BIO Web Conf.
Volume 8, 2017
2016 International Conference on Medicine Sciences and Bioengineering (ICMSB2016)
|
|
|---|---|---|
| Article Number | 02009 | |
| Number of page(s) | 6 | |
| Section | Session II: Bioinformatics | |
| DOI | https://doi.org/10.1051/bioconf/20170802009 | |
| Published online | 11 January 2017 | |
Toxicology evaluation of selenium protein powder
1 College of Animal Science and Veterinary Medicine, Tianjin Agricultural University, Tianjin 300384 China
2 Tianjin Selenium Egg Biological Technology Co., Ltd., Tianjin 300100, China
a Corresponding author: hbmjfts@126.com
The experiment was conducted to evaluate the safety of selenium protein powder, a novel organic selenium nutritional supplement, and reported corresponding data and results based on a series of toxicological tests. It was examined to evaluate oral acute toxicity by median lethal dose test and mutagenic potential by bone marrow cell micronucleus test and sperm abnormality test using Kun-Ming mice. The results showed that the oral LD50 of selenium protein powder exceeded 31.25 g/kg body weight in mice. No mutagenicity was found by mouse bone marrow cell micronucleus test and mouse sperm abnormality test. The results suggested greater safety of selenium protein powder as a nutritional selenium supplement, and selenium protein powder has the potential for development and application in food systems or functional foods.
© The Authors, published by EDP Sciences, 2017
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