Study of the antimicrobial activity of the drug "DB" when exposed to various test surfaces

Federal Center for Toxicological, Radiation and Biological Safety, Laboratory of Cell Cultures and Nutrient Media, 420075 Kazan, Russia

^* Corresponding author: evgenechka1885@gmail.com

Abstract

This paper presents the results of a study of the antimicrobial activity of the drug «DB» when exposed to various test surfaces. Among the many reasons for the occurrence of mass lesions of the fingers and hooves of cattle, one of the main ones is the untimely provision of veterinary and zootechnical care to animals with limb injuries and the inadequate sanitary and hygienic condition of the floor coverings of premises, leading to rapid infection and illness of a large number of animals. The active and excipients of the developed medicinal product «DB» are inexpensive and widely available on the country’s market: bentonite, copper sulfate, zinc sulfate, polyvinyl alcohol, perlite, camphor oil and sodium benzenesulfochloramide. Material costs and time for organizing therapeutic and preventive measures using «DB» are minimal and are combined with the production process, which allows for the systematic prevention and treatment of finger diseases at the very beginning of the development of the pathological process, thereby significantly reducing the concentration of microorganisms in the wound area and floor coverings, effectively preventing the development of infection. Based on the results of laboratory studies, it was shown that «DB» has antimicrobial activity against gram-negative and gram-positive bacteria, as well as fungicidal activity and, in the future, will help not only reduce the incidence of disease in livestock, but also significantly reduce the microbial load on the floor coverings of livestock buildings.