BIO Web Conf.
Volume 20, 20201st International Conference on Tropical Wetland Biodiversity and Conservation (ICWEB 2019)
|Number of page(s)||5|
|Section||Wetland Plant and Microbes Biodiversity|
|Published online||01 June 2020|
The Antibacterial Activity of Actinomycetes Against the Growth of Streptococcus mutans and Lactobacillus acidophilus
1) Departement of Biomedic Faculty of Dentistry Lambung Mangkurat University, Banjarmasin
2) Departement of Biology Oral Faculty of Dentistry Lambung Mangkurat University, Banjarmasin
3) Departement of Endodontics Faculty of Dentistry Lambung Mangkurat University, Banjarmasin
4) Departement of Microbiology Parasitology Faculty of Medical Lambung Mangkurat University, Banjarmasin
* Corresponding author: firstname.lastname@example.org
Antibacterial compounds are generally produced from many herbal ingredients, but antibacterials may be produced from soil microbes, one of which is Actinomycetes. Actinomycetes are a soil bacterium capable of producing secondary metabolites in the form of antibacterial compounds. The antibacterial compound has the potential as an alternative antibacterial agent against oral microbes. One of the oral microbes that have a major role in the occurrence of caries is Streptococcus mutans and Lactobacillus acidophilus. This study aimed to analyze the antibacterial activity of Actinomycetes against the growth of S. mutans and L. acidophilus Actinomycetes extracts at the concentration of 0.625%, 1.25%, 2.5%, 5%, 10%, 20%, and 40% were respectively exerted as the treatment groups while 0.12% Chlorhexidine Gluconate (CHX) and aquadest as control. The measurement of antibacterial activity is done by looking at MIC and MBC. One Way ANOVA and Post Hoc Dunnets T3 test MIC and MBC values show p=0,000 (p <0.05). Actinomycetes extract at the concentration of 0.625% was able to inhibit the growth of S. mutans and L. acidophilus which was determined as the MIC and at the concentration of 40% as MBC of S.mutans and the concentration of 10% as MBC of L. acidophilus. There was an antibacterial activity of Actinomycetes to the growth of S. mutans and L.acidophilus.
© The Authors, published by EDP Sciences, 2020
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