BIO Web Conf.
Volume 20, 20201st International Conference on Tropical Wetland Biodiversity and Conservation (ICWEB 2019)
|Number of page(s)||4|
|Section||Wetland Plant and Microbes Biodiversity|
|Published online||01 June 2020|
The Benefits of Chalcone and Its Derivatives as Antibacterial Agents: A Review
Departemen of Chemistry, Faculty of Mathematics and Natural Science, Lambung Mangkurat University Jl. A. Yani Km.35.8. Banjarbaru, South Kalimantan, Indonesia
* Corresponding author: firstname.lastname@example.org
Chalcone is a secondary metabolite compound found in plants. Chalcones contain two aryl rings, namely ring A and B which connected to the α,β unsaturated ketones. Chalcone derivatives are synthesized by various substituent groups in both rings, as well as the types of rings. These variations make chalcone and its derivatives, have interesting bioactivity, one of which is antibacterial. This review is considered the chalcone-derived compounds that have antibacterial bioactivity, including methoxy, hydroxy, prenyl, and halogen groups in ring A or B. Besides, there are two forms of these rings as well such as pyrroly l-furany l-chalcones and indoly l-thiopheny l-chalcone. We hope this review is useful for the development of the synthesis of organic compounds and the discovery of new drug design.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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