| Issue |
BIO Web Conf.
Volume 65, 2023
EBWFF 2023 - International Scientific Conference Ecological and Biological Well-Being of Flora and Fauna (Part 2)
|
|
|---|---|---|
| Article Number | 05042 | |
| Number of page(s) | 8 | |
| Section | Preventive Healthcare and Urban Ecology | |
| DOI | https://doi.org/10.1051/bioconf/20236505042 | |
| Published online | 04 September 2023 | |
The Role of curcumin extract in Ameliorating Cyclophosphamide-Induced Cardiotoxicity
1 University of Kufa, Faculty of Veterinary Medicine, Iraq
2 University of Kufa, Faculty of Science, Department of Biology, Iraq
* Corresponding author: halab.albayati@uokufa.edu.iq
Cyclophosphamide, a chemotherapeutic and immunosuppressive drug, has been linked to problems after bone marrow transplantation in the past. More recently, it has been demonstrated that cardiotoxicity limits the dose of cyclophosphamide, and cardiology is receiving more attention. Though the exact mechanism of cyclophosphamide-induced cardiotoxicity is unknown, oxidative and nitrative stress are suspected to play a role. As a result, the focus of this review is on antioxidants and how they can reduce or prevent cyclophosphamide-induced cardiotoxicity. It will place a special emphasis on the cardioprotective properties of naturally occurring, plant-derived antioxidants such as curcumin extract, which have recently attracted a lot of interest.
© The Authors, published by EDP Sciences, 2023
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