Open Access
| Issue |
BIO Web Conf.
Volume 187, 2025
2025 Joint Meeting of International Conference of Nutritional Fortification (ISPH-ISNPR 2025)
|
|
|---|---|---|
| Article Number | 05004 | |
| Number of page(s) | 6 | |
| Section | Pharmacology and Phytochemistry | |
| DOI | https://doi.org/10.1051/bioconf/202518705004 | |
| Published online | 09 September 2025 | |
- Y. Pang, J. Xiong, Y. Wu, W. Ding A review on recent advances on nobiletin in central and peripheral nervous system diseases. Eur. J. Med. Res. 28, 485 (2023). ttps:doi: 10.1186/s40001-023-01450-7. [Google Scholar]
- Y. Cheng, S. Feng, C. Sheng, C Yang, Y Li Nobiletin from citrus peel: a promising therapeutic agent for liver disease-pharmacological characteristics, mechanisms, and potential applications. Front Pharmacol. 15, 1354809 (2024) https:doi:10.3389/fphar.2024. [Google Scholar]
- A. Watanabe, N. Natsume, T. Nakamura, H. Watanabe, M. Kurawaka, W. Kobayashi, A. Yamano, T. Teruya, T. Yonezawa, J. T. Woo, The production of polymethoxyflavones-rich Kaempferia parviflora extract and its biological activities. J. Jap. Soc. Med. Use of Funct. Foods. 15, 396–404 (2021). (in Japanese) [Google Scholar]
- S. Yamada, M. Shirai, K. Ono, T. Teruya, A. Yamano, J. T. Woo., Beneficial effects of a nobiletin-rich formulated supplement of Sikwasa (C. depressa) peel on cognitive function in elderly Japanese subjects; A multicenter, randomized, double-blind, placebo-controlled study. Food Sci. Nutr. 9, 6844–6853 (2021). https:/doi:10.1002/fsn3.2640. [Google Scholar]
- B. He, K. Nohara, N. Park, Y-S Park, B. Guillory, Z. Zhao, J. Garcia, N. Koike, C. C. Lee, J. S. Takahashi, S-H Yoo, Z. Chen, The small molecule nobiletin targets the molecular oscillator to enhance circadian rhythms and protect against metabolic syndrome. Cell Metab. 23, 610–621 (2016). https:/doi:10.1016/j.cmet.2016.03.007. [Google Scholar]
- M. Wenzhe, S. Feng, Z. Yao, Z. Yuan, L. Liu, Y. Xie, Nobiletin enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cancer cell. Sci. Rep. 5, 18789 (2015). https:/doi:10.1038/srep18789. [Google Scholar]
- A. Nakajima, Y. Ohizumi, Potential benefits of nobiletin, a citrus flavonoid, against Alzheimer’s disease and Parkinson’s disease. Int. J. Mol. Sci. 20, 3380 (2019). https:/doi:10.3390/ijms20143380. [Google Scholar]
- T. Asakawa, A. Hiza, M. Nakayama, M. Inai, D. Oyama, H. Koide, K. Shimizu, T. Wakimoto, N. Harada, H. Tsukada, N. Oku, T. Kan, PET imaging of nobiletin based on a practical total synthesis. Chem. Commun (Camb). 47, 2868–2870 (2011). https:/doi:10.1039/c0cc04936k. [Google Scholar]
- D. Saigusa, M. Shibuya, D. Jinno, H. Yamakoshi, Y. Iwabuchi, A. Yokosuka, Y. Mimaki, A. Naganuma, Y. Ohizumi, Y. Tomioka, T. Yamakuni, Highperformance liquid chromatography with photodiode array detection for determination of nobiletin content in the brain and serum of mice administrated the natural compound. Anal. Bioanal. Chem. 400, 3635–3641 (2011). https:/doi:10.1007/s00216-011-5031-2. [Google Scholar]
- S. Zhang, Y. Tomata, K. Sugiyama, Y. Sugawara, I. Tsuji I, Citrus consumption and incident dementia in elderly Japanese: the Ohsaki Cohort 2006 Study. Br. J. Nutr. 117, 1174–1180 (2017). https:/doi:10.1017/S000711451700109X. [Google Scholar]
- T. Seki, T. Kamiya, K. Furukawa, M. Azumi, S. Ishizuka, S. Takayama, S. Nagase, H. Arai, T. Yamakuni, N. Yaegashi, Nobiletin-rich citrus reticulata peels, a kampo medicine for Alzheimer’s disease: a case series. Geriatr. Gerontol. Int. 13, 236–238 (2013). https:/doi:10.1111/j.1447-0594.2012.00892.x. [Google Scholar]
- F. Niwa, M. Kondo, K. Sakurada, M. Nakagawa, J. Imanishi, T. Mizuno, Regional cerebral blood flow in [123]I-IMP single-photon emission computed tomography and the Wechsler memory scale-revised in nondemented elderly subjects with subjective cognitive impairment. Intern. Med. 55, 3571–3578 (2016). https:/doi:10.2169/internalmedicine.55.6725. [Google Scholar]
- S. Yamada, Y. Kato. Effects of saw palmetto extract on the vanilloid receptor TRPV1. Low. Urin. Tract. Symptoms. 14, 117–121 (2022). https:/doi:10.1111/luts.12413. [Google Scholar]
- Sugaya, S. Nishijima, K. Kadekawa, K. Ashitomi, K. Kawahara, J. T. Woo, Clinical study on efficacy and safety of peucedanum japonicum, Nobiletin and tomato lycopene mixture for lower urinary tract symptoms. Shinryo to Shinyaku (Med Cons NewRemed). 57, 501–511 (2020). (in Japansese) [Google Scholar]
- Sugaya, S. Nishijima, K. Kadekawa, K. Ashitomi, K. Kawahara, J. T. Woo, Clinical study on efficacy and safety of nobiletin, kaempferia parviflora, and peucedanum japonicum mixture for lower urinary tract symptoms. Shinryo to Shinyaku (Med Cons New-Remed). 57, 923–929 (2020). (in Japansese) [Google Scholar]
Current usage metrics show cumulative count of Article Views (full-text article views including HTML views, PDF and ePub downloads, according to the available data) and Abstracts Views on Vision4Press platform.
Data correspond to usage on the plateform after 2015. The current usage metrics is available 48-96 hours after online publication and is updated daily on week days.
Initial download of the metrics may take a while.

